@Article{ZambiancoSOCZSBKBJ:2020:DeTaPh,
               author = "Zambianco, Naiara A. and Silva, Vinicius A. O. P. da and Orzari, 
                         Luiz O. and Corat, Evaldo Jos{\'e} and Zanin, Hudson G. and 
                         Silva, Tiago A. and Buller, Gary A. and Keefe, Edmund M. and 
                         Banks, Craig E. and Janegitz, Bruno C.",
          affiliation = "{Universidade Federal de S{\~a}o Carlos (UFSCar)} and 
                         {Universidade Federal de S{\~a}o Carlos (UFSCar)} and 
                         {Universidade Federal de S{\~a}o Carlos (UFSCar)} and {Instituto 
                         Nacional de Pesquisas Espaciais (INPE)} and {Universidade Estadual 
                         de Campinas (UNICAMP)} and {Federal Center for Technological 
                         Education of Minas Gerais} and {Manchester Metropolitan 
                         University} and {Manchester Metropolitan University} and 
                         {Manchester Metropolitan University} and {Universidade Federal de 
                         S{\~a}o Carlos (UFSCar)}",
                title = "Determination of tadalafil in pharmaceutical samples by vertically 
                         oriented multi-walled carbon nanotube electrochemical sensing 
                         device",
              journal = "Journal of Electroanalytical Chemistry",
                 year = "2020",
               volume = "877",
                pages = "e114501",
                month = "Nov.",
             keywords = "Tadalafil, Electrochemistry, Vertically oriented multi-walled 
                         carbon nanotube, Sensor, Pharmaceutical formulation.",
             abstract = "In this work, an electrochemical sensor based on vertically 
                         oriented carbon nanotubes (voMWCNT), electrically wired via 
                         connection upon a copper plate, for the detection of tadalafil 
                         (TD) is reported. The voMWCNT is easily prepared via microwave 
                         plasma reactor with no additional post-treatment. The voMWCNT was 
                         characterized by scanning and transmission electron microscopy in 
                         addition to electrochemical characterization with cyclic 
                         voltammetry. Once TD is of easy access and used in the treatment 
                         of erectile dysfunction and related diseases, the quality control 
                         of this drug is of high importance. Using linear sweep 
                         voltammetry, the detection of TD was found to be possible from 
                         0.85 to 8.9 \μmol L\−1 , with an R2 of 0.992 with a 
                         limit of detection found to correspond to 78 nmol L\−1 . 
                         The quantification of TD in different pharmaceutical drugs, as 
                         well as the device stability, indicates that the voMWCNT has 
                         potential for the routine sensing of TD.",
                  doi = "10.1016/j.jelechem.2020.114501",
                  url = "http://dx.doi.org/10.1016/j.jelechem.2020.114501",
                 issn = "0022-0728",
             language = "en",
           targetfile = "zambianco_determination.pdf",
        urlaccessdate = "12 maio 2024"
}